Abstract
Metamizole, a widely used analgesic and antipyretic, has been associated with rare but potentially life-threatening hematological adverse reactions, such as agranulocytosis. This case report highlights the diagnostic complexity and clinical management of a patient who presented with neutropenic fever and concurrent multidrug-resistant infections, ultimately found to be related to metamizole-induced agranulocytosis. It underlines the importance of considering drug-induced causes in the differential diagnosis of agranulocytosis and stresses the relevance of early identification and prompt discontinuation of the causative agent.