Systematized Linear Porokeratosis With Palmoplantar and Nail Involvement: A Rare Presentation

掌跖及指甲受累的系统性线状角化过度症:一种罕见的表现

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Abstract

Porokeratosis encompasses a group of genetically and clinically heterogenous dermatoses characterized by abnormal epidermal keratinization, with the cornoid lamella being the hallmark histological feature. Linear porokeratosis, a rare variant of porokeratosis, typically manifests early in life, with lesions that follow the lines of Blaschko and carry the highest risk of malignancy transformation. Here, we present a case of systematized linear porokeratosis in a 48-year-old male with childhood onset, notable for the rare co-existence of palmoplantar and nail involvement. This report emphasizes the importance of long-term surveillance in patients with linear porokeratosis due to its malignant potential.

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