Abstract
PURPOSE OF REVIEW: In this review, the promising benefits of coffee in terms of its composition, anticancer mechanisms, and effects on digestive system cancers are highlighted and suggestions for future research are given. RECENT FINDINGS: Coffee is one of the most widely consumed beverages in the world. Chlorogenic acid, caffeine, cafestol, kahweol, phenolic compounds, alkaloids, trigonelline, and other secondary metabolites in its composition have positive effects on health. Colorectal cancer, esophageal cancer, liver cancer, gastric cancer, and pancreatic cancer are among the most common cancers of the digestive system worldwide. Cancer risk is increasingly influenced by dietary factors. SUMMARY: Coffee has been linked to potential protective effects against cancer due to its antioxidant, anti-inflammatory, antifibrotic, and antiangiogenic properties, as it contains over 1,000 bioactive compounds. However, there are inconsistent findings concerning coffee consumption and the risk of digestive tract cancers and more clinical studies with larger samples are needed.