Abstract
Sensor-based data collection of human behaviour (digital phenotyping) enables real-time monitoring of behavioural and physiological markers. This emerging approach offers immense potential to transform mental health research and care by identifying early signs of symptom exacerbation, supporting personalised interventions, and enhancing our understanding of daily lived experiences. However, despite its promise, technical and user-experience challenges limit its effectiveness. This Perspective critically examines these challenges and provides standardisation strategies, including universal protocols and cross-platform interoperability. We propose the development of universal frameworks, adoption of open-source APIs, enhanced cross-platform interoperability, and greater collaboration between academic researchers and industry stakeholders. We also highlight the need for culturally sensitive and user-centred designs to improve equity and engagement. By addressing these gaps, standardisation can enhance data reliability, promote scalability and maximise the potential of digital phenotyping in clinical and research mental health settings.