Abstract
OBJECTIVE: To investigate the characteristics of early pregnancy cardiometabolic index in patients with hypertensive disorder complicating pregnancy (preeclampsia) and its correlation with the occurrence of different degrees of preeclampsia. METHODS: This retrospective study enrolled 210 pregnant women with preeclampsia, who were registered and delivered at Beijing Haidian District Maternal and Child Health Hospital, as the preeclampsia group. Another 210 healthy pregnant women with similar gestational age during the same period were selected as the control group. Early pregnancy clinical data, including body mass index (BMI), blood pressure, waist circumference, triglyceride level, and cardiometabolic index, were compared between the two groups. The relationship between early pregnancy cardiometabolic index and the occurrence of preeclampsia was analyzed. RESULTS: As the cardiometabolic index quartile increased, the proportion of preeclampsia patients showed a significant upward trend (trend Z=34.006, P<0.001). For each additional standard deviation (SD) unit of cardiometabolic index, the risk of preeclampsia increased by 24.245 times (95% CI: 8.359-70.321). After adjusting for age, weight, BMI, waist circumference, and gestational age, the risk of preeclampsia (SD units of cardiometabolic index) was 5.986 times higher (P<0.05). CONCLUSION: Early pregnancy cardiometabolic index is positively correlated with the occurrence of preeclampsia.