Abstract
INTRODUCTION: Current guidelines recommend using high-intensity statins in patients with atherosclerotic cardiovascular disease (ASCVD). Guideline directed statin intensity (GDSI) implementation and ASCVD outcomes may differ by sex. We evaluated sex-based differences in GDSI use and recurrent ASCVD outcomes in a large healthcare network. METHODS: Using electronic medical records, we assessed statin use and intensity in a cohort of patients with established coronary artery disease (coronary artery bypass grafting or percutaneous coronary intervention) between 2010-2022. Statins were categorized into GDSI (high intensity),