Abstract
Disclosure: C. won-kyoung: None. B. Eunha: None. S. Sim: None. S. Park: None. S. Kim: None. S. Kim: None. M. Ahn: None. S. Kim: None. K. Cho: None. K. Han: None. M. Jung: None. B. Suh: None. OBJECTIVE To explore the incidence of emergency hospitalization among young-onset diabetes using a nationwide registry database. RESEARCH DESIGN AND METHODS Based on the Korean National Health Insurance Service-National Sample Cohort database from 2006 to 2019, data were collected for patients aged ≤30 years with type 1 (T1D) and type 2 diabetes (T2D). The risks of emergency hospitalization were compared with those in the general population. Results: The study consisted of 512,756 participants. T1D and T2D were detected in 428 and 1,298 participants, respectively. After adjusting for sex, age and family income, the hazard ratios (HRs) of any emergency hospitalization were 4.70 (95% confidence interval [CI], 4.07–5.44) and 3.43 (95% CI, 3.07–3.83) for T1D and T2D, respectively. The HRs of emergency hospitalization due to endocrine problems were 439.53 (95% CI, 341.32–566.00) and 57.06 (95% CI, 36.97–88.06) for T1D and T2D, respectively. The HRs of emergency hospitalization due to cardiovascular problems were 3.67 (95% CI, 1.38–9.80) and 6.02 (95% CI, 3.86–9.38) for T1D and T2D, respectively. The HRs of emergency hospitalization due to infective disorders were 3.48 (95% CI, 2.06–5.87) and 4.72 (95% CI, 3.41–6.53) for T1D and T2D, respectively. The HRs of emergency hospitalization due to cancer were 2.57 (95% CI, 0.36–18.26) and 5.57 (95% CI, 2.63–11.81) for T1D and T2D, respectively. Conclusions: In South Korea, patients with young-onset diabetes are at high risk of emergency hospitalization for various reasons. Presentation: Saturday, July 12, 2025