Fertility Complications After Uterine Artery Embolization for Postpartum Hemorrhage: A Case of Infertility and Miscarriage Following Stillbirth

产后出血行子宫动脉栓塞术后生育并发症:一例死产后不孕和流产病例

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Abstract

Uterine artery embolization (UAE) is widely used as a minimally invasive treatment for postpartum hemorrhage (PPH), with the expectation of preserving fertility. However, its effects on fertility remain unclear. We present the case of a 32-year-old woman who developed secondary infertility after undergoing UAE for severe PPH following a stillbirth at 37 weeks of gestation. Despite the resumption of regular menstruation, the endometrium remained persistently thin, and hysterosalpingography revealed narrowing of the uterine cavity. She underwent assisted reproductive technology (ART), but repeated frozen-thawed embryo transfer (FET) cycles resulted in implantation failure. Although she eventually conceived, she experienced a missed abortion at seven weeks. No specific causes for the miscarriage were identified. This case highlights that even in the absence of intrauterine adhesions or amenorrhea, endometrial thinning and uterine cavity narrowing after UAE can contribute to infertility and miscarriage. UAE should be carefully considered in women desiring future pregnancies, and alternative hemostatic measures should be prioritized when possible. Further research is required to improve UAE techniques and fertility preservation.

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