Abstract
INTRODUCTION: Acne vulgaris is a chronic skin condition affecting adolescents and adults, often prompting patients to seek complementary and alternative medicine (CAM) due to dissatisfaction with conventional treatments. CAM usage is shaped by cultural beliefs and accessibility, but data in Saudi Arabia remain limited. METHODOLOGY: A cross-sectional study was carried out in Al-Ahsa (2024-2025) through an online questionnaire targeting Saudi adults (≥18 years) diagnosed with acne vulgaris. RESULTS: Among 322 respondents, most were aged 18-25 (64.0%) and female (67.1%). Traditional treatments were previously used by 70.5%, mostly topical medications (67.7%), but only 30.3% reported satisfaction. CAM awareness was found in 53.1%, and 44.4% had previously used CAM, primarily nutritional supplements (35.8%). CAM use was significantly associated with age and prior traditional treatment. Side effects were reported by 23.8%, mainly redness (82.5%). Side effects had a higher rate among traditional treatment users. Satisfaction with CAM was significantly linked to acne duration, and history of traditional treatment, though only 19.6% reported satisfaction. In the regression model, older age, adequate acne-related information, and experiencing side effects significantly increased CAM use, while experiencing side effects and family history predicted lower satisfaction with CAM. CONCLUSION: The study revealed moderate CAM use among acne patients, with nutritional supplements being the most common, with limited satisfaction and some reported side effects. Overall satisfaction with CAM remained low, emphasizing the need for better guidance and integration of safe, evidence-based alternative therapies in acne care.