Multiunit and oscillatory activity in macaque V1 is modulated by blinking in a context-dependent way

猕猴V1区的多单元和振荡活动会受到眨眼的调节,且这种调节方式取决于上下文。

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Abstract

Eye blinks modulate neural activity in visual areas even if the visual input is unchanged. Is the influence of blinking defined by the motor output of the blink? We analyzed blink-related neural activity with laminar resolution in V1 of two macaque monkeys in two conditions, viewing a video and at rest. During free viewing a video, blinks induced a modulation of the local field potential (LFP) in the theta, beta, and gamma band with a granular/infragranular focus. The multiunit activity (MUA) decreased around blink execution. Surprisingly, when comparing the results to blinks executed during the rest condition, we found that MUA increased around blinks. The blink-related LFP power changes, while increasing after a blink in both conditions, were significantly different in amplitude and latency. Our findings show that the blink induced modulation of V1 activity is not determined by the motor execution but depends on the condition in which the movement is executed. This suggests that interactions between movement and neural processes in sensory areas are context-dependent. These interactions may play an important role in predictive coding within the framework of active sensing.

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