Abstract
Multinucleate cell angiohistiocytoma (MCAH) is a rarely reported and likely underdiagnosed cutaneous entity with benign biological behavior. MCAH is described as a solitary or multiple proliferation of vascular and fibrohistiocytic origin, with largely unknown etiopathogenesis. It presents as red-brown to violaceous papules or nodules, mainly on the extremities, and is usually asymptomatic. A definitive diagnosis of MCAH requires specific histopathological and immunohistochemical findings. The following report presents a case of solitary MCAH with the aim of clarifying the clinical, histological, and especially dermoscopic aspects of this dermatological disorder, which may resemble more aggressive skin tumors.