Abstract
Sickle cell disease (SCD) is an inherited disorder that affects the shape of red blood cells. Spontaneous orbital hematoma is an uncommon complication of SCD. This complication is serious and can affect the visual prognosis. Imaging (computed tomography scan and especially the magnetic resonance imaging) is crucial to diagnose orbital hematomas; it also helps eliminate other causes of rapidly progressive exophthalmos. The management of orbital hematomas in these patients is medical, but a surgical intervention can be necessary. This case highlights the diagnosis and management of this rare complication.