Abstract
An odontogenic epithelium-derived developing cyst of the mandible is known as an odontogenic keratocyst (OKC). According to the World Health Organization (WHO) classification from 2005, OKCs were referred to as keratocystic odontogenic tumors (KCOTs) and were thought to be cystic neoplasms. As of 2017, the WHO again switched KCOT back to OKC, as there was a lack of support for their justification as a tumor entity. This article presents a rare case report of single and multiple OKCs located in both the maxilla and mandible in male and female pediatric patients, demonstrating conservative as well as surgical management of OKCs. A dentigerous cyst was the provisional diagnosis in all three instances based on clinical and radiographic evidence. We planned both conservative and surgical treatment after considering the type and size of the lesion in the respective cases. A tissue specimen was then sent for histological examination, which confirmed our provisional diagnosis. Histological findings revealed a parakeratinized stratified epithelial lining with a thick columnar basal cell layer, surface corrugation, and neutrophils and lymphocytes organized against extravasated red blood cells (RBC), which confirmed the diagnosis of OKC in all three patients. Clinically and radiographically, OKC might resemble other benign, less aggressive tumors. Thus, it's critical to distinguish them from other cysts and tumors in order to provide appropriate care and lower the risk of recurrence. HOW TO CITE THIS ARTICLE: Dua R, Gangwar A, Singh HP, et al. Clinicopathological Correlation of Pericoronal Radiolucency in Pediatric Patients. Int J Clin Pediatr Dent 2025;18(3):321-326.