Medication Use Patterns, Polypharmacy, and Potentially Inappropriate Medications among Institutionalized Older Adults in East Coast Malaysia: A Cross-sectional Study

马来西亚东海岸养老机构老年人用药模式、多重用药及潜在不适宜用药情况:一项横断面研究

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Abstract

OBJECTIVE: Older adults need comprehensive healthcare with particular attention to medication management to prevent drug-related problems while ensuring optimal therapeutic outcomes. This study aims to assess the pattern of medication use, prevalence of polypharmacy, and the use of potentially inappropriate medications (PIMs) based on the 2023 American Geriatrics Society Updated Beers Criteria(®). METHODS: This cross-sectional study gathered demographic and medication use data from older adults (n = 73) at an institutional care facility in East Coast Malaysia, who met the inclusion criterion of taking at least one medication. Patterns of medication use, prevalence of polypharmacy, and PIM use were examined descriptively, while their associations with demographic characteristics were analyzed using IBM SPSS(®) Version 26 software. FINDINGS: The mean age of this population was 72 ± 9.07 years, with the majority being Malays (83.6%), males (50.7%), Muslims (86.3%), single (53.4%), bedbound (75.3%), and they were dependent on caretakers for their daily activities (75.3%). Polypharmacy occurred in approximately one-fifth of the population (21.9%). The most commonly prescribed medications were lipid-modifying agents and antihypertensives, followed by antiplatelet agents, anti-diabetic agents, and Vitamin B and iron supplements. Identified PIMs include prazosin, colchicine, lorazepam, and chlorpromazine, each prescribed to a minority of residents. CONCLUSION: The prevalence of polypharmacy in this study was moderate, reflecting the need for continued attention to medication management among institutionalized older adults. Despite the low prevalence of PIM, regular monitoring remains essential to minimize adverse drug reactions and improve the quality of care for this population.

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