Diagnostic Cutoff Values of Aortic Valve Coefficient (AVC) in Relation to Aortic-Valve Area and Calcium Score: A Patient-Level Analysis

•AVC combines pressure drop and flow to quantify aortic stenosis severity.•Classification-tree analysis defined AVC thresholds relative to aortic valve area.•AVC cutoffs stratify mild, moderate, and severe AS.•AVC differentiates paradoxical and classical low-flow, low-gradient AS.•AVC enables integrated assessment of AS severity across flow states.