An In Vivo Study to Compare and Evaluate the Antimicrobial Efficacy and pH Change of GC Tooth Mousse and Curodont(TM) Protect against Streptococcus mutans

一项体内研究比较和评估了GC牙齿慕斯和Curodont™对变形链球菌的抗菌功效和pH值变化保护作用

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Abstract

AIM AND BACKGROUND: Dental caries is the most prevalent oral healthcare problem worldwide, especially in pediatric patients. To manage dental caries, typical oral hygiene methods are not enough in many cases. So as to regenerate the tooth structure, remineralization is required. Thus, the aim of this in vivo study was to evaluate the antimicrobial efficacy and salivary pH change with Curodont(TM) Protect and compare it with an effective remineralizing agent, GC Tooth Mousse. MATERIALS AND METHODS: Both the GC Tooth Mousse (group I) and the Curodont(TM) Protect remineralizing agent (group II) were tested in an in vivo investigation to determine their antibacterial activity against Streptococcus mutans. Calculating the total viable bacterial colonies by visual inspection with a HiMedia Laboratories Private Limited digital colony counter (LA6660) for statistical analysis allowed us to estimate the antibacterial effectiveness.We used a pocket pH meter to measure the pH of saliva both before and after the treatment. The parametric tests of significance (Wilcoxon paired test/paired t-test) were used for inferential statistics. RESULTS: The presample count of GC Tooth Mousse and Curodont(TM) Protect was compared and was found to be nonsignificant with a p-value of 0.7. The postsample count of GC Tooth Mousse and Curodont(TM) Protect, on the other hand, was shown to be statistically significant (p < 0.001). The pre- and post-pH of GC Tooth Mousse and Curodont(TM) Protect was compared and was found to be nonsignificant with a p-value of 0.1. CONCLUSION: When tested against S. mutans, the Curodont(TM) Protect tooth remineralizing agent proved to be more effective than the GC Tooth Mousse remineralizing agent. HOW TO CITE THIS ARTICLE: Sharma M, Garg P, Vats V, et al. An In Vivo Study to Compare and Evaluate the Antimicrobial Efficacy and pH Change of GC Tooth Mousse and Curodont(TM) Protect against Streptococcus mutans. Int J Clin Pediatr Dent 2026;19(2):156-163.

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