Abstract
Populations at higher risk for Alzheimer's disease and related dementias (ADRD) are often not proportionally represented in research. These populations include but are not limited to individuals from wide-ranging ethnic and racial backgrounds, those with lower education, and those with limited health-care access. Addressing disparities in research participation will be essential to improving our understanding of the varied causal mechanisms, risks and protective factors, and responses to interventions to find generalizable solutions to improve health outcomes in ADRD. The goals of this perspective are to (1) review obstacles and facilitators to recruitment and retention of populations at higher risk for ADRD, (2) provide an overview of data-driven actionable items, ongoing strategies, and proposed initiatives for the recruitment and retention of these populations in National Institute on Aging-funded Alzheimer's Disease Research Centers; and (3) highlight the roles of Outreach, Recruitment and Engagement Cores and the National Alzheimer's Coordinating Center in achieving these goals.