Abstract
OBJECTIVE: To explore the effect of a multimodal interventions (MI) on postoperative sleep and recovery quality in patients undergoing laparoscopic surgery for colorectal cancer (CRC). METHODS: 266 patients with CRC undergoing laparoscopic surgery were randomly divided into MI (intervention group) and control (control group) groups. Postoperative treatment in control group was carried out according to medical standards, while MI was provided based on routine treatment in intervention group. The sleep at night before surgery (N(-2)) after surgery (N(0)), and 6th night after surgery (N(6)) were collected. The Pittsburgh Sleep Quality Index (PSQI) and 15 Recovery Quality Inventory (QoR-15) scores on the 1st day before surgery (D(-1)) and after surgery (D(1)), and the 7th day after surgery (D(7)) were collected. The postoperative complications and NRS pain scores from days 1-3 (D(1-3)) were collected. RESULTS: At N(6), patients in control group had increased awake time, decreased sleep time, and decreased sleep efficiency after falling asleep than intervention group (P < 0.05). Compared with D(-1), both groups of patients showed an increase in PSQI scores at D(1) and D(7), while a decrease in QoR-15 scores (P < 0.05). Compared with control group, intervention group had a shorter latency period for falling asleep at N(0) (P < 0.05). At D(1) and D(7), the PSQI score was lower and the QoR-15 score was higher (P < 0.05). At D(1) and D(2), the NRS pain score during exercise was lower and satisfaction was higher (P < 0.05). CONCLUSION: In patients with laparoscopic surgery for colorectal cancer, MI can improve postoperative sleep, recovery quality, and postoperative recovery.