Abstract
Left atrial myxomas are rare, benign cardiac tumors that are often asymptomatic but may present with systemic embolic events. We report the case of a middle-aged man who presented with acute ischemic stroke, which led to the diagnosis of a left atrial myxoma. Further evaluation revealed associated infective endocarditis and critical limb ischemia, secondary to systemic embolization. The patient underwent successful surgical excision of the tumor, with multidisciplinary management. This case highlights the importance of considering cardiac sources in embolic stroke of unclear origin and underscores the need for prompt diagnosis and coordinated care to prevent severe complications.