A primer on sequencing and genotype imputation in cattle

牛测序和基因型推断入门指南

阅读:1

Abstract

Since their introduction to the beef industry, genotyping technologies have opened the door for genomic selection and accelerated population improvement. Single-nucleotide polymorphism arrays have served as the backbone of genomic selection programs since their introduction. Developments in sequencing and genotype imputation offer alternatives to array-based genotyping that have the potential to provide orders of magnitude more information at a lower cost. In this review, I give an overview of array-based genotyping, genomic sequencing, low-pass sequencing, and imputation. Additionally, I provide perspectives on how low-coverage sequencing and imputation could simultaneously drive genomic discovery and be used for routine genotyping as sequencing costs continue to decline.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。