Isolated Duodenal Variceal Hemorrhage: A Rare and Unusual Presentation in Newly Diagnosed Cirrhosis

Duodenal varices are a rare cause of upper gastrointestinal bleeding and are typically seen in the setting of portal hypertension along with adjacent esophageal or gastric varices. Isolated duodenal varices without concurrent varices elsewhere are uncommon and pose significant diagnostic and therapeutic challenges. We report a case of an elderly woman who presented anemic and with coffee-ground emesis and was found to have newly diagnosed cirrhosis with isolated bleeding duodenal varices successfully managed with endoscopic clipping followed by coil embolization performed by interventional radiology.