Primordial Odontogenic Tumor Associated with Impacted Supernumerary Tooth: First Case Report and an Updated Review of Literature

与阻生多生牙相关的原始牙源性肿瘤:首例病例报告及文献综述

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Abstract

Primordial Odontogenic Tumor (POT) is an exceptionally rare benign odontogenic lesion derived from embryonic dental tissues, characterized by primitive odontogenic epithelium and fibrous stroma resembling early tooth development stages. This case report presents a 17-year-old male with malaligned teeth in the lower jaw, where radiographic examination revealed an ill-defined radiolucent lesion associated with an impacted supernumerary tooth. A provisional diagnosis of a dentigerous cyst was made, followed by surgical enucleation and extraction. Histopathological analysis confirmed POT, marking the 27th documented case and the first involving a supernumerary tooth. The lesion exhibited typical histopathological features, including odontogenic epithelium surrounded by fibro myxomatous stroma with plump fibroblasts resembling dental papilla. Complete surgical excision was curative, with no recurrence observed after a 7-month follow-up. This case highlights the importance of recognizing the unique clinical and histological features of POT for accurate diagnosis and management, emphasizing the need for comprehensive evaluation of rare odontogenic lesions.

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