Abstract
Leiomyosarcomas (LMS) arise from smooth muscle and represents only 6% of all sarcomas. LMS originating from major blood vessels, called vascular LMS, are detected mostly in the inferior vena cava. Arterial LMS are a rarity. We present a 43-year-old patient with a LMS arising from the left external iliac artery. The patient was referred to us with symptoms of left lower abdominal pain extending to the left limb and underwent a contrast computed tomography which suggested a suspicious mass near the left iliac vessels. She underwent laparoscopic excision of the tumour, whose histological examination revealed an LMS G2 arising from the external iliac artery. Immunohistochemically CD34, p53, Desmin, as well as smooth muscle actin, tested positive.