Abstract
RATIONALE: Glomus tumors (GTs) are painful and typically benign neoplasms found in the subungual region of the fingertips. However, the occurrence of multiple GT within nerve fascicles in the scapular region is rare. PATIENT CONCERNS: A 41-year-old male presented with a 5-year history of progressive tenderness in the scapular region, accompanied by elevated local skin temperature. Magnetic resonance imaging revealed a small abnormal signal measuring approximately 3.1 × 3.0 mm, appearing hypoechoic on T1 and hyperechoic on T2 images, with clear boundaries. The lesion was initially diagnosed as an inflammatory lesion. DIAGNOSES: Multiple intraneural GT located within different nerve fascicles were diagnosed based on immunohistochemical analysis and hematoxylin-eosin staining. INTERVENTIONS: The nodules were completely excised. OUTCOMES: One week later, the patient reported significant pain relief compared with preoperative symptoms. LESSONS: To the best of our knowledge, this is the first documented case of multiple intraneural GTs occurring within 3 different nerve fascicles to highlight the importance of accurate diagnosis to prevent misdiagnosis.