Kikuchi-Fujimoto disease: 6 years old boy rare case in Syria

菊池-藤本病:叙利亚一名6岁男孩的罕见病例

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Abstract

Kikuchi-Fujimoto disease (KFD) is a rare condition first identified in Japan in 1972. It typically presents with high fever and lymph node swelling, and may be linked to autoimmune conditions or viral infections. A 6-year-old boy presented with cervical enlargement and recurrent high fever. Physical examination revealed enlarged lymph nodes in the neck, axillary, and inguinal regions, along with hepatosplenomegaly. CT scans confirmed widespread lymphadenopathy, and blood tests showed elevated white blood cell count and C-reactive protein levels. Although lymphoma was suspected, biopsies indicated atypical lymphadenitis. Despite a positive Epstein-Barr virus test, no treatment was effective. Further lymph node biopsies ruled out lymphoma, EBV, and TB, ultimately confirming Kikuchi-Fujimoto Disease.

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