Abstract
Surgery for centenarians comes with unprecedented challenges and risks. The limited physical reserve and fragility of homeostatic control in this population reduces their ability to adapt to physiological changes encountered during open and laparoscopic surgery. This case report presents a 108-year-old female patient who underwent laparoscopic resection of a symptomatic gastric gastrointestinal stromal tumour (GIST), without any adverse effects. The case highlights the importance of thorough preoperative risk assessment and planning, multidisciplinary input, and individualised patient care.