Abstract
PURPOSE: To compare refractive, visual, and safety outcomes of 3 methods for surgical correction of aphakia: anterior chamber intraocular lens (AC IOL), intrascleral haptic fixation intraocular lens (ISHF-IOL), and Gore-Tex suture fixation of modified eyelet toric intraocular lens (GSF-MET IOL). SETTING: Tertiary care academic center. DESIGN: Multisurgeon retrospective case series. METHODS: Review of 357 eyes undergoing one of the above 3 techniques between 2017 and 2024. Comparative refractive (defocus [spherical equivalent (SE)], astigmatism [refractive cylinder (RefCyl)], and blur [defocus equivalent]), visual acuity (corrected distance visual acuity [CDVA]), and safety outcomes (cystoid macular edema and return to the operating room [ROR] events) were recorded. Owing to concerns about IOL tilting with one of the models, a subgroup analysis was performed on 2 IOL models within the ISHF group. Statistical analyses included descriptive statistics, chi-square tests, 1-way analysis of variance, and 2-sample t testing. RESULTS: All 3 groups had similar SE ( P = .87), RefCyl ( P = .91), and CDVA in eyes without significant comorbidities ( P = .23). ROR was similar among all groups ( P = .08). Within the ISHF-IOL group, CT Lucia 602 and Sensar AR40 had similar SE and RefCyl ( P = .18 and P = .15, respectively). CDVA was similar in eyes without significant comorbidities for both IOL models ( P = .70). ROR was significantly higher with CT Lucia 602 than with Sensar AR40 ( P = .03). CONCLUSIONS: All 3 surgical techniques can provide good refractive, visual acuity, and safety outcomes. Within the ISHF-IOL group, the Sensar AR40 had lower ROR rates than the CT Lucia 602, with similar CDVA outcomes.