Abstract
At a clinical research hospital, the Department of Perioperative Services has recently implemented an opioid-free anesthesia protocol for selected patients undergoing robotic-assisted prostatectomy. This protocol incorporates intraoperative infusions of ketamine, lidocaine, and magnesium as part of a multimodal analgesic strategy. The present case report describes an unusual occurrence of postoperative delirium in this context and aims to provide educational insights into its clinical presentation, contributing factors, and management.