Abstract
Hemophagocytic syndrome (HPS) is a common complication in pediatric populations but a rare disease in adults. Also known as hemophagocytic lymphohistiocytosis (HLH), the few cases reported in adults have been primarily caused by severe infections and hematologic malignancies. We highlight the importance of considering HPS as a differential diagnosis in patients with persistent inflammatory conditions. This report describes the aggressive clinical course of a 58-year-old female patient. Prompt recognition of HPS may improve outcomes in such cases.