From structural pangenomes to functional panomics in plants

从植物的结构泛基因组学到功能泛组学

阅读:1

Abstract

Understanding how genome structure and gene content evolve within and among plant species requires analytical frameworks that capture the full spectrum of allelic and structural variation. Plant pangenomes have progressed from gene-focused and linear representations to chromosome-scale, haplotype-resolved graphs that preserve allelic and structural diversity across populations. Attention is increasingly focused on the evolutionary processes that generate and maintain pangenome architecture, alongside the adoption of graph-based coordinate systems that reduce reference bias and enable multi-omics integration. Here, we review plant pangenome paradigms, from early homology-based gene sets to haplotype-resolved graph models, and summarize tradeoffs in construction, mapping, and variant analysis. We synthesize patterns of core and variable gene compartments across studies and examine how transposable elements, gene duplication, and selection shape their contrasting evolutionary dynamics. Using panNLRomes and crop domestication as case studies, we illustrate how graph-based frameworks clarify evolutionary and functional signals obscured by single references, including birth-death dynamics at resistance loci and structural variants associated with domestication. Finally, we discuss emerging applications in pantranscriptomics and panepigenomics and outline key methodological and infrastructural challenges.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。