Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study

Among this prospective cohort of 93 Ugandan adults who survived HIV-associated cryptococcal or tuberculous meningitis, baseline secondary cerebrospinal fluid (CSF) HIV viral escape was highly prevalent and was associated with better neurocognitive outcomes at 3 months. Individuals with secondary CSF HIV viral escape were more likely to be antiretroviral therapy-naïve and to exhibit CSF pleocytosis.