Abstract
COVID-19 can present with gastrointestinal symptoms in infants; an uncommon presentation may be intussusception. There are rarely reported cases of intussusception due to COVID-19 in the literature. Of the reported cases, only one case presented with bilious emesis. Bilious emesis is an atypical manifestation of intussusception and is more commonly linked to malrotation. We report an additional case of COVID-19-related intussusception, which presented with bilious emesis. Although the prior case required surgical intervention, our case was treated successfully with an air enema reduction. These cases highlight bilious vomiting as a possible presentation of COVID-19-related intussusception and warrant inclusion of COVID-19 in the differential diagnosis of severe intussusception in infants.