Abstract
Intradialytic hypotension (IDH) is a common and potentially severe complication of hemodialysis, usually caused by poor ultrafiltration prescriptions or inappropriate dry weight determination. Nevertheless, its relation with dialysis-independent causes cannot be ruled out. This case report presents a 35-year-old woman undergoing chronic hemodialysis for lupus nephropathy, who experienced IDH secondary to an unusual manifestation of spontaneous splenic rupture (SSR). We report the clinical presentation, workup, and management of this infrequent but potentially life-threatening syndrome.