Mucin degradation by Bifidobacterium strains isolated from the human intestinal microbiota
从人体肠道菌群中分离的双歧杆菌菌株降解粘蛋白
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作者：Patricia Ruas-Madiedo, Miguel Gueimonde, María Fernández-García, Clara G de los Reyes-Gavilán, Abelardo Margolles
Abstract
The presence of the genes engBF (endo-alpha-N-acetylgalactosaminidase) and afcA (1,2-alpha-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The expression of both genes was highly induced in the presence of mucin.
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