Copper borate (CuB(4)O(7))-promoted multi-component green synthesis of 2,4,5-triarylimidazole derivatives and evidence of in situ conversion of copper borate (CuB(4)O(7)) into Cu(OAc)(2) in the presence of NH(4)OAc

铜硼酸盐 (CuB₄O₇) 促进的多组分绿色合成 2,4,5-三芳基咪唑衍生物,并证实了在 NH₄OAc 存在下铜硼酸盐 (CuB₄O₇) 原位转化为 Cu(OAc)₂

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Abstract

A green, efficient, and straightforward methodology for the three-component synthesis of 2,4,5-triarylimidazole has been developed under solvent-free conditions using unconventional CuB(4)O(7) as a promoter. This green approach encouragingly provides access to a library of 2,4,5-tri-arylimidazole. Also, we have been able to isolate the compound (5) and (6) in situ, which provides an insight into the direct conversion of CuB(4)O(7) into copper acetate in the presence of NH(4)OAc under solvent-free condition. The main advantage of this protocol includes an easy reaction procedure, short reaction time, and easy work up of the product without using any tedious separation method.

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