[Clinical characteristics of 91 patients of otorhinolaryngology head and neck malignant tumors in children]

【91例儿童耳鼻咽喉头颈部恶性肿瘤患者的临床特征】

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Abstract

Objective:To analyze the clinical characteristics, treatment and prognosis of the otolaryngology head and neck malignant tumors in children, in order to improve the diagnosis and treatment of the diseases. Methods:The patients of otorhinolaryngology head and neck malignant solid tumors under 14 years old hospitalized in Kunming Children's Hospital and the First Affiliated Hospital of Kunming Medical University from 2014 to 2020 were retrospectively analyzed. All cases were statistically analyzed according to gender, age, location, pathological type and treatment method. Results:The main clinical manifestations of 91 children were mainly facial and neck masses, including nasal congestion, swallowing discomfort, and continuous intermittent fever. CT and MRI examination showed that the diameter of the tumor was 1.2 cm ×2.0 cm to 5.0 cm×12.0 cm, with a mean of 2.8 cm×3.2 cm, and 19 cases had distant metastasis. The main tissue sources were soft tissue (56 cases) and epithelial tissue (35 cases). There were 6 pathological types, the most common was sarcoma (41 cases), followed by neuroblastoma (15 cases), papillary carcinoma (14 cases), squamous cell carcinoma (10 cases), mucoepidermoid carcinoma (8 cases), and adenocarcinoma (3 cases). According to the classification of tissue origin, the statistical analysis of gender and pathological type showed statistically significant differences in both gender and pathological types(P<0.01). Conclusion:The age of onset, primary site, tissue origin and pathological type of otolaryngology head and neck malignancy in children have their own characteristics, which should be comprehensively evaluated and treated with multidisciplinary treatment.

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