Surveillance and genetic characterization of Listeria monocytogenes in the food chain in Montenegro during the period 2014-2022

2014-2022年黑山食品链中单增李斯特菌的监测和基因特征分析

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Abstract

INTRODUCTION: Listeria monocytogenes is an ubiquitous foodborne pathogen that represents a serious threat to public health and the food industry. METHODS: In this study Whole Genome Sequencing (WGS) was used to characterize 160 L. monocytogenes isolates obtained from 22,593 different food sources in Montenegro during the years 2014-2022. RESULTS: Isolates belonged to 21 different clonal complexes (CCs), 22 sequence types (STs) and 73 core genome multilocus sequence types (cgMLST) revealing a high diversity. The most prevalent STs were ST8 (n = 29), ST9 (n = 31), ST121 (n = 19) and ST155 (n = 20). All isolates carried virulence genes (VGs), 111 isolates carried mobile genetic elements (MGEs) (ranging from 1 to 7 MGEs) and 101 isolates carried plasmids (ranging from 1 to 3 plasmids). All isolates carried the intrinsic resistance genes fosX and lin. None of the isolates carried acquired antimicrobial resistance genes (ARGs). DISCUSSION/CONCLUSION: Continuous monitoring and surveillance of L. monocytogenes is needed for improving and ameliorating the public health.

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