Comparison of Perichondrium Reinforcement and the Use of a Cartilage-Perichondrium Composite Graft Alone in the Repair of Subtotal Perforation: A Semi-Random Study

比较软骨膜加固与单独使用软骨-软骨膜复合移植修复次全穿孔的效果:一项半随机研究

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Abstract

ObjectiveGraft outcomes and complications were compared in patients who received a cartilage-perichondrium composite graft via perichondrium reinforcement (CPPR) and those treated using only a cartilage-perichondrium composite graft underlay (CPGU) technique, including raising a tympanomeatal flap, in the repair of a subtotal perforation.Materials and MethodsPatients with subtotal perforations were semi-randomly allocated to the CPPR and CPGU groups. The graft success rate, hearing outcomes, operation times, postoperative visual analog scale (VAS) values, and complications were compared for up to 6 months postoperatively.ResultsThe sample consisted of 67 ears from 67 patients. The mean operation time was 33.1 ± 2.8 min in the CPPR group and 56.2 ± 1.8 min in the CPGU group. At 6 months postoperatively, the VAS scores were 1.4 ± 0.9 and 3.7 ± 1.2, and the graft success rates were 97.0% and 88.2% (P = .371), respectively. There were no significant differences in the mean gain in the air-bone gap (16.2 ± 5.3 vs. 14.7 ± 6.2) between the two groups, but hearing improvement was greater in the CPPR group. Ear fullness was reported by 21.2% patients in the CPPR group and 91.2% of patients in the CPGU group. Temporary hypogeusia developed in 3.0% of patients in the CPPR group and 38.2% of those in the CPGU group. Myringitis was seen in 9.1% patients in the CPPR group and 2.9% in the CPGU group.ConclusionIn patients undergoing subtotal perforation repair, the 6-month graft outcome in patients treated with the perichondrium reinforcement technique without raising a tympanomeatal flap and external ear canal packing was similar to that of patients who underwent a flap-raising technique. The advantages of the perichondrium reinforcement technique are that it is simple, time-saving, and minimally invasive, with less ear fullness and better hearing recovery.

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