Abstract
BACKGROUND: Platelet count (PLT) has been identified as a predictor for the development of pelvic adhesions. However, it remains unclear whether platelet-related parameters can also serve as indicators for the occurrence of intrauterine adhesions (IUA). METHODS: Patients diagnosed with IUA were included for further analysis, with platelet-related parameters assessed through routine blood tests. The predictive value of PLT and platelet hematocrit (PCT) was evaluated using receiver operating characteristic (ROC) curve analysis. Recurrence of IUA was determined based on a one-year follow-up. RESULTS: Our study included 69 IUA patients and 60 matched healthy women. We found that PLT and PCT levels were significantly elevated in IUA patients compared to the healthy controls. ROC analysis demonstrated that both PLT and PCT effectively predicted the occurrence of IUA. Additionally, higher PLT and PCT levels were noted in patients with recurrent IUA, suggesting their potential for predicting recurrence. CONCLUSION: Elevated PLT and PCT levels were observed in patients with IUA and were further increased in those with recurrent cases. These findings suggest that high PLT and PCT levels may serve as valuable predictors for both the occurrence and recurrence of IUA. Specifically, the study is limited by the small sample size of recurrent IUA cases and potential confounders. These limitations should be considered when interpreting the findings.