Abstract
Freeman-Sheldon syndrome (FSS) is a rare congenital disorder with craniofacial and musculoskeletal abnormalities, presenting unique orthodontic challenges due to microstomia and restricted oral access. This case report describes the successful non-surgical orthodontic management of a 15-year-old girl with severe crowding using pre-adjusted edgewise appliances. Favorable alignment and functional occlusion were achieved, and a customized retention protocol combining Essix and fixed lingual retainers ensured stability.