Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto's Disease

1型血清阴性自身免疫性胰腺炎:一例罕见的合并硬化性胆管炎和桥本氏病的自身免疫性胰腺炎病例

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Abstract

Autoimmune pancreatitis (AIP) is very rarely reported in the literature. It is one of the immunoglobulin-G (IgG) related diseases that commonly presents with abdominal pain, mass, jaundice, and weight changes. The disease also has extrapancreatic manifestations, of which the most common is autoimmune sclerosing cholangitis. We report a case of autoimmune pancreatitis that was further found to be associated with Hashimoto's thyroiditis and sclerosing cholangitis. The clinical manifestations vary and it is important to exclude pancreatic malignancy before diagnosing any patient with AIP. Although further studies need to be done, currently the treatment of choice is steroid therapy. Physicians should also screen patients for other autoimmune diseases to rule out any concern.

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