Noninvasive serum biomarkers for liver steatosis in nonalcoholic fatty liver disease: Current and future developments

非酒精性脂肪肝疾病中肝脂肪变性的无创血清生物标志物:现状与未来发展

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Abstract

Nonalcoholic fatty liver disease (NAFLD) affects approximately 30% of the population worldwide and includes nonalcoholic fatty liver, nonalcoholic steatohepatitis (NASH), and cirrhosis. Since NAFLD-associated diseases begin with steatosis, the early diagnosis of steatosis helps to prevent the progression of NASH and fibrosis. In addition, more convenient and easily diagnosable serum biomarkers are becoming crucial in disease diagnosis. In this report, we summarize the known serum biomarkers for liver steatosis and provide guidance for their application in clinical practice.

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