Abstract
May-Thurner syndrome (MTS) is a pathological variant where the left iliac vein is compressed by the right iliac artery. Usually common in females between the third and fourth decades of life, this case report is about MTS in an adolescent girl. The patient was overweight and had a sedentary lifestyle. She developed a sudden onset of unilateral left leg deep venous thrombosis (DVT), leading to low-risk pulmonary embolism (PE) within a week of the symptoms starting. The patient received a heparin infusion for one week, after which she was switched to subcutaneous low-molecular-weight heparin. Apart from the initial high D-dimer, the rest of the thrombophilia workup was unremarkable. The whole exome sequencing (WES) study was negative. An inferior vena cava (IVC) filter was not advised for her due to the small size of the clot and her age. The patient responded well to heparin alone and was discharged home on enoxaparin.