Abstract
Cutaneous squamous cell carcinoma-keratoacanthoma (cSCC-KA) is a benign but aggressive neoplasm arising from keratinizing epidermal cells. In this case, we report a 56-year-old man who developed a KA on the right second toe after experiencing a minor trauma to the same region, without osteolysis or nodal invasion. Second toe amputation was performed under sedation. Our case highlights the features of cSCC-KA, its association with trauma, and the importance of early diagnosis and treatment.