Detection of Rickettsia spp in ticks by MALDI-TOF MS

使用 MALDI-TOF MS 检测蜱中的立克次体

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作者:Amina Yssouf, Lionel Almeras, Jérôme Terras, Cristina Socolovschi, Didier Raoult, Philippe Parola

Background

Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has been shown to be an effective tool for the rapid identification of arthropods, including tick vectors of human diseases. Methodology/principal findings: The

Significance

Taken together, the present work demonstrates the utility of MALDI-TOF MS for a dual identification of tick species and intracellular bacteria. Therefore, MALDI-TOF MS is a relevant tool for the accurate detection of Rickettsia spp in Ticks for both field monitoring and entomological diagnosis. The present work offers new perspectives for the monitoring of other vector borne diseases that present public health concerns.

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