Abstract
Monkeypox (Mpox) was declared a public health emergency in 2022. The most common form of presentation is a self-limited illness associated with a skin rash. However, immunocompromised patients may present with more severe forms of the disease. We present the case of an immunocompromised patient diagnosed with Mpox, who, in addition to presenting the characteristic skin lesions, also exhibited gastrointestinal involvement and incidental tomographic findings of pulmonary involvement due to the virus.