Abstract
Background In the current era of reconstructive surgery, microvascular free flap transfers are the most popular reconstructive procedures performed. The main reason for the failure of the flap and re-exploration is venous thrombosis. Traditionally, most surgeons prefer performing two-vein anastomoses. There is insufficient literature to support that dual-venous anastomosis is better than single-venous anastomosis. In this study, we compared the success rate of single-venous anastomosis with dual-venous anastomosis of different free flap reconstructions. Methodology The retrospective cohort study was conducted with a total of 101 patients. Eighty-three were in the one-vein group, and the remaining 18 were in the two-vein group. Outcomes were compared between the two groups regarding re-exploration and flap failure. Results The overall success rate of free flap reconstruction was 96%. Among the 101 free flaps, 16 flaps had signs of venous compromise and were re-explored. Out of the 16 flaps, 11 flaps (13.2%) were in the one-vein group, and 5 flaps (27.7%) were in the two-vein group. In the two-vein group, 100% of the flaps were salvaged, and in the one-vein group, only 63% of the flaps were salvaged after re-exploration. There was no statistically significant difference between the one-vein group and the two-vein group concerning re-exploration. Conclusions The rate of re-exploration was lower in the one-vein group when compared to the two-vein group. However, this difference was not statistically significant. Hence, a single-vein anastomosis is sufficient for a successful microvascular free flap. However, the rate of flap salvage is better with two-vein anastomosis if there is venous congestion.