Prevalence of spondyloarthritis in Terceira, Azores: a population based study

亚速尔群岛特塞拉岛脊柱关节炎患病率:一项基于人群的研究

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作者:J Bruges-Armas, C Lima, M J Peixoto, P Santos, D Mendonça, B Martins da Silva, G Herrero-Beaumont, A Calin

Conclusion

These data complement previous studies in European countries on SpA prevalence and establish an estimate of the overall prevalence of SpA in a southern European population.

Methods

Study subjects were recruited from people over the age of 50 years from one half of the island of Terceira (n=24 561). Seventy eight men and 78 women from each five year age group were selected, giving a total of 468 men and 468 women available for study, of whom 490 agreed to take part. These subjects were assessed by dorsal, lumbar, and pelvic radiography. Radiological sacroiliitis was identified in eight patients on whom sacroiliac computed tomography scans were performed. HLA class I typing by polymerase chain reaction with sequence-specific primers was carried out in seven cases.

Objective

To determine the prevalence of spondyloarthritis (SpA) in the Caucasian population of Terceira Island, Azores.

Results

SpA was present in eight subjects (1.6%, 95% CI 0.8 to 2.7%), including seven men (2.7%) and one woman (0.4%). Three (1.2% ) male patients with definite ankylosing spondylitis were HLA-B27 positive. Only one person had a previous diagnosis of SpA.

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