Abstract
Large defect of the lip and buccal mucosa created due to wide resection of the cancer is difficult to reconstruct and always a challenge. Such defects are complex as there is loss of outer skin, muscle, soft tissue, and inner mucosal lining. We report the use of submental artery island flap (SAIF) in the reconstruction of a large defect of oral commissure and buccal mucosa in a 70-year-old female with the diagnosis of verrucous carcinoma. The final outcome was optimal in terms of cosmetic and functional results. We obtained good lip seal without any problem in speech and swallowing. SAIF is an excellent alternative option for reconstruction of large complex defects of lips and oral commissure. It has a reliable vascular supply and provides a thin and pliable tissue for reconstruction in such critical area of face.