Abstract
Carpal tunnel syndrome is an entrapment neuropathy of median nerve in wrist presenting with symptoms like pain, numbness, and paresthesia in hand and lateral three fingers. Conservative treatments are effective for mild to moderate cases, whereas severe or refractory carpal tunnel syndrome may require surgical intervention. Hydrodissection, a technique involving the separation of the nerve from surrounding tissues, has emerged as a minimally invasive and effective treatment option for carpal tunnel syndrome, leading to faster recovery and lower complication. In this case report, a 48 years female with two years history of severe pain and paresthesia in right hand, underwent ultrasound-guided hydrodissection of median nerve with 5% dextrose. Following intervention, the patient reported decreased symptoms and expressed satisfaction with the treatment during subsequent follow-up after 2 weeks. Ultrasound-guided hydrodissection of median nerve with 5% dextrose is effective treatment modality for patients with failed conservative management of carpal tunnel syndrome.